Personalised Medicine

Choosing the right test for you

We are all unique individuals that require unique healthcare interventions.  We definitely cannot benefit from generic practices.

DNA testing allows us to better understand our response to different diet, lifestyle and supplement choices (nutrigenics) as well as their response to certain medications (pharmagenomics)

You are born with a set of genes that you cannot change during your lifetime.  You can however influence the manner in which these genes are expressed and therefore change how things work to your body's advantage, but first you need to know what needs changing.

There is a strong relationship between the genes we carry and the nutritional, medicinal and lifestyle changes we make

So which test is right for you?

Whilst there is a great range of tests (some of which also include key elements of others), sometimes having two or three tests can give you the all the answers.  

Unless you are 100% sure, we always recommend having an online consultation with our lead practitioner Lilly Wickham, who can advise which tests will give you the results you seek.  If you are an existing client, talk to Lilly in your next session.

 

DNA Core

DNA Core is the starting point on your journey to personalised healthcare. This test reports on gene-environment interactions and provides personalised, easy-to-follow, summarised recommendations on four core areas:

  1. key biological processes that drive health including methylation, detoxification and lipid metabolism
  2. macro- and micronutrient requirements based on genetic response
  3. weight management insights such as obesity risk and eating behaviour
  4. exercise responsiveness including power and endurance potential, and recovery time.

Note that this test includes all gene variants tested and insights reported in DNA Health, DNA Diet, and DNA Sport, in one user-friendly report. 

This test is £395.  To order this test, please call or WhatsApp us on 07956004434

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DNA Health

The DNA Health test is designed to optimise well-being and health by personalising lifestyle and diet choices and, where necessary, using supplements tailored to offset any particular nutritional deficit based on specific gene variants.

The DNA Health approach assists the healthcare practitioner in establishing the optimal nutrition necessary for good health, longevity and disease risk mitigation. Diet is a key factor in determining genomic stability as it impacts on all relevant pathways:  exposure to dietary carcinogens, biotransformation, DNA repair and synthesis, and apoptosis. Current recommended dietary allowances for vitamins and minerals are based largely on the prevention of diseases of deficiency. However, because diseases of lifestyle are partly caused by damage to DNA it stands to reason that we should focus our attention on defining optimal requirements of key minerals and vitamins for preventing genomic instability.

Additional attention should be paid to individuals with genetic polymorphisms that alter the bioavailability of specific micro-nutrients and the affinity of specific key enzymes for their micro-nutrient co-factor.

Clinical Value

  • Highlights specific metabolic pathways that may require extra support
  • Provides recommendations that involve optimisation of quantities of certain nutrients, vitamins and minerals
  • Suggests whether an individual is better able to reduce their cholesterol levels through diet, as opposed to through medication
  • Provides an indication of the degree of susceptibility to the harmful effects of carcinogens ingested in the diet

The DNA Health Test Report provides: 

  • The level of impact of any genetic variants identified
  • An explanation of their impact on health
  • Appropriate nutritional and lifestyle recommendations

 

The results are divided in sections of key metabolic function, so that genetic weaknesses and strengths within a functional area can be easily identified.

This test is £225.  To order this test, please call or WhatsApp us on 07956004434

 

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DNA Diet

One of the first products of its kind in the world, DNA Diet tests for 15 genes that impact metabolism and exercise. The genes comprising the DNA Diet test have associations with body weight and body mass index,  and all meet stringent criteria for utility in genetic screening tests.  We provide a detailed report with recommendations that include dietary changes and an exercise programme.

Genes involved in regulation of energy expenditure, appetite, and fat metabolism, all play an important role in weight regulation. In fact 40% to 80% of the variance in body weight is due to genetic factors. This helps to explain why not everyone gains or loses weight while following the same diet, despite being exposed to similar environments. Identifying an individual’s responsiveness to diet and lifestyle modification to control weight can be extremely advantageous.

Genetics determines an individual’s susceptibility to obesity when exposed to an unfavourable environment. It also explores the way a person responds to diet and exercise.

While healthy nutrition may in certain cases result in weight loss, this depends on many factors. The DNA diet provides a tailor made nutrition and exercise programme. Healthy eating and exercise may result in weight loss, but this is not guaranteed.


Clinical Value

  • Provides strategies for weight management based on genetic make-up
  • Provides motivation to individuals with a goal to lose weight
  • Provides an understanding of why previous weight management programmes may have  been unsuccessful
  • Provides insight to which diet type (i.e. Mediterranean style, low carbohydrate, low fat diet) may be most suited to an individual to manage weight, based on genotype 

The DNA Diet Test Report provides:

  • The level of impact of any genetic variants identified 
  • An explanation of their impact on weight management
  • Appropriate nutritional and lifestyle recommendations.  This includes weight management priorities, diet plan principles, exercise planning and how to calculate MET hours

This test is £185.  To order this test, please call or WhatsApp us on 07956004434

 

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DNA Sport

DNA Sport examines various biological areas that impact training responsiveness and sporting performance. These include soft tissue and bone formation and remodelling; inflammation; oxidative stress; oxygenation influenced by blood flow and respiration; energy and fuel production; and metabolism during exercise. Knowledge of gene variations that influence these key biological areas can be used to exploit any genetic advantages and identify any weaknesses that need to be supported, through diet and the training strategies.

Clinical Value

Suitable for the recreational athlete and the elite performance athlete, it provides information to optimise:

  • Power and endurance – physiological factors
  • Structural integrity – tendon pathology and injury risk
  • Recovery – training patterns and nutrition


The DNA Sport Test Report provides:

  • The level of impact of any genetic variants identified
  • An explanation of their impact on sport performance, injury and recovery risk
  • Appropriate nutritional and lifestyle recommendations in relation to health and sports  performance, including power and endurance, athletic potential and key training principles, injury and recovery

This test is £185.  To order this test, please call or WhatsApp us on 07956004434

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DNA Active

DNA Active® is a genetic test designed to guide the personalisation of training and nutritional recommendations to optimise athletic performance. It provides insight into power and endurance potential, genetic risk for soft tissue injuries and how to ensure optimal recovery time between high intensity sessions.

This test is a combination of DNA Sport & DNA Diet tests, created to assist designing of unique and effective training & nutrition programmes.

The DNA Active report is your handy reference guide to weight management, exercise responsiveness, nutrient requirements, and a host of other factors that will combine to help you reach your performance goals.

The DNA Active test was created to assist trainers and coaches in designing unique and effective training and nutrition programmes, optimised to assist clients in accomplishing their performance and weight loss goals.

The test is suitable for the elite performance athlete as well as the recreational athlete looking to maximise their fitness potential and reach peak levels of conditioning.

This test is £185.  To order this test, please call or WhatsApp us on 07956004434

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DNA Skin

The future of skincare aims at a personalised treatment strategy, based on information relating to your individual biochemistry and genetic inheritance. DNA Skin analyses variations on 18 genes associated with the following key areas involved in skin health and aging: collagen formation; protection from SUN & UV exposure; inflammation; protection from oxidative stress. From the information your DNA Skin test reveals, personalised lifestyle, nutrition, nutraceutical and cosmeceutical recommendations can be given for improved skincare and to decrease the visible signs of aging.

This test is £185.  To order this test, please call or WhatsApp us on 07956004434

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DNA Mind

DNA mind reports on associations in the following areas: 

  • Neurodegenerative disorders – mild cognitive decline & late onset Alzheimer’s disease,
  • Mood disorders – Depressive disorder, bipolar disorder, anxiety disorder & post-traumatic stress disorder
  • Addictive behaviour – Risk for alcohol, nicotine, cannabis & opioid dependence, psychosis response from cannabis use, eating disorders (binge eating), ‘adrenaline seeking’/risk-taking behaviour 

Neuropsychiatric disorders account for up to 25% of all disability-adjusted life years (Gatt et al 2015.). Whilst the heritability of these mental disorders is significant, environmental factors also play a key role in their aetiology. Genetic variations involved in key biological processes that contribute toward the risk of development of mental health disorders may give insight to the prevention, diagnosis and treatment of the disease.

The DNA mind test analyses 30 genes which have been shown to have significant associations with key mental health disorders.Clinical Value

Knowledge of an individual’s genotype will provide diagnostic insight and assist in determining optimal treatment strategies for individuals suffering from, or at risk for, mental health disorders.

Genes included in the test are involved in key biological areas related to mental health. These areas include: 

  • Lipid metabolism
  • Inflammation
  • Methylation
  • Neurotrophic, dopaminergic & serotonergic pathways
  • Endo-cannabinoid pathway
  • Cell-signalling 

DNA mind Report Provides: Identification of the level of impact of any genetic variants

An explanation of their impact on the specific biochemical areaAn explanation of each area’s impact on mental health  

This test is £185.  To order, please call or WhatsApp us on 07956004434

 

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DNA 'GrowBaby'

This test gives insight into key biological areas relating to maternal and fetal health.

It provides guidance on how mums-to-be can improve fertility, identify reasons why you have had difficulty getting pregnant and optimise their health, using gene-based personalised diet, supplement and lifestyle interventions from pre-conception to birth and beyond.

Growbaby is a genetic test for mum-to-be, designed to help you better understand the functioning of key biological pathways that influence maternal and fetal health, and how these relate to the major birth phenotypes.

The report provides valuable insights into how you can optimise health outcomes for mom and baby using gene-based personalised diet, supplement, and lifestyle interventions.

Preconception and the perinatal time period provide a unique opportunity to establish the foundations for optimum health and development across the lifespan.

Targeted interventions, using insights from a genetic test, can optimise the health of the mother, supporting a healthier pregnancy, and resulting in transgenerational health and resilience. “healthy mum – healthy baby – healthy world”

This test is £185.  To order this test, please call or WhatsApp us on 07956004434

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DNA Oestrogen

 

Guides personalisation of diet, hormone and nutritional supplement recommendations to improve oestrogen metabolism.

DNA Oestrogen includes 11 genes involved in oestrogen biosynthesis, oestrogen metabolism, and phase I and phase II detoxification, providing information to guide personalised diet, lifestyle, hormone, and nutra-ceutical recommendations.

Approximately 80% of breast cancer occurs in women with no family history.  Oestrogen affects the function of a number of target tissues and research has shown that an increased lifetime exposure to oestrogen is a strong risk factor in the development of breast cancer. DNA Oestrogen tests for gene variants that have been shown to have an impact on how oestrogen is metabolised. Guiding the personalisation of diet, hormone and nutritional supplement recommendations, based on the insight gained from the DNA Oestrogen test, to improve oestrogen metabolism is of benefit to men and women who suffer from numerous oestrogen-dominant conditions and who have higher lifetime exposure to oestrogens, oestrogen metabolites and other carcinogens.

Clinical Value:

Recommended for:

  • Men or women with a strong family history of breast, ovarian, colon or prostate cancer
  • Women who suffer from oestrogen-dominant conditions such as endometriosis, premenstrual syndrome and uterine fibroid tumours
  • Women considering oral contraceptives, hormone replacement therapy or bio-identical hormone supplementation
  • Women who are considering in vitro fertilisation or who have been diagnosed with oestrogen  receptor-positive breast cancer


The DNA Oestrogen Test Report provides:

  • The level of impact of any genetic variants identified
  • An explanation of their impact on oestrogen metabolism
  • Appropriate nutritional and lifestyle recommendations to support healthy oestrogen metabolism

This test is £185.  To order this test, please call or WhatsApp us on 07956004434

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DNA Smile

DNA Smile is a genetic test designed to give insights into the state of your oral health and your predisposition for developing periodontal disease, tooth caries and other systemic diseases.

DNA Smile reports on 20 gene variations involved in the key biological areas including Innate immunity, Inflammation and acquired immunity, Sweet-tooth predisposition, Detoxification, Lipid metabolism – all of which are central in the management of periodontal and systemic health. 

The DNA Smile report offers targeted, personalised diet, nutraceutical, lifestyle, and oral health recommendations to offset possible genetic weaknesses and optimise oral and systemic health outcomes.

The DNA Smile test provides key insights into the functioning of biological areas*; innate and acquired immunity and inflammation, as well as sweet tooth. DNA Smile Plus also provides insight into lipid metabolism, and detoxification – all of which are central in the management of periodontal and systemic health. 

Why the test was developed/clinical utility

There is a rapidly growing body of evidence that supports the link between risk for periodontal disease and the development of other chronic diseases including cardiovascular disease, diabetes, certain cancers, and cognitive decline.

Having insight into how gene variants involved in key biological areas will impact oral health can guide better clinical decision making in order to improve oral health outcomes, but also to optimise overall systemic health.

"Our mouth is not just for smiling, our teeth can do more than chew, and our tongues do more than just taste and swallow. The oral cavity is a sensitive ecosystem and the gateway to our body. We feed ourselves through the mouth, we speak to others through it - and it is central to the health of the entire body. If the mouth is not healthy, diseases develop: from irritability, tiredness and obesity to cardiovascular diseases to strokes, Alzheimer's and cancer - everything begins in the mouth. “ Extract from the German dentist book

“A healthy mouth leads to a healthy body”

“Good oral health is the start to good health”

“Your health begins in the mouth – It is the doorway to the entire body”.

“What happens in the mouth, does not stay in the mouth”

This test is £185.  To order this test, please call or WhatsApp us on 07956004434

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DNA Resilience

What is the test

DNA Resilience is a genetic test targeted at individuals who want to:

 

  1. Lead more effectively (in business, sport and life)
  2. Cope better under stressful and demanding conditions 
  3. Enhance their mental, emotional and physical health
  • Live up to their fullest potential  

 

DNA Resilience reports on the seven key molecular areas that have the greatest influence on resilience. They are:

 

  • Cortisol, oxytocin, the neurotrophic pathway, neuropeptide Y, norepinephrine, dopamine, and serotonin

 

The report is able to determine an individuals’ genetic potential for resilience and provide ways in which intrinsic strengths can be amplified and existing weaknesses reduced. The action steps centre on highly individualised lifestyle strategies that leverage diet, targeted activity, environmental awareness, and nutritional supplements. 

 

Why the test was developed/clinical utility

 

The test was developed to combat the challenges brought on by the current set of socioeconomic conditions (global economic downturn, social isolation, health insecurity etc.) and the dire impact these have on our emotional, mental and physical health.

 

Given the hereditability of emotional regulation (30%), temperament (±56%) and cognitive aptitude (>99%), a critical knowledge and understanding of individual genetics and environmental influences can unlock exceptional resilience and a performance advantage regardless of circumstances. 

 

‘From potential to performance’.

‘From surviving to thriving

This test is £238.  To order this test, please call or WhatsApp us on 07956004434

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DNA Risk

DNA Risk: HLA-Related Autoimmunity looks at gene variants related to common autoimmune diseases and provides healthcare practitioners ‘diagnostic insight’ for patients already suffering from an autoimmune disorder, or who are identified as at-risk due to a family history of disease and exposure to environmental risk factors. This test analyses thousands of gene variants within the MHC and HLA gene region to report on HLA types, specific to HLA class I (HLA-A, -B, -C), and HLA class II (HLA-DPA1, -DPB1, -DQA1, -DQB1, -DRB1, -DRB3, -DRB4, and -DRB5) loci, and MHC related gene variants associated with common autoimmune diseases.

THE AUTOIMMUNE DISEASES DISCUSSED IN THIS REPORT INCLUDE:


• Alopecia areata (AA)
• Ankylosing spondylitis (AS)
• Coeliac disease (CD)
• Graves’ disease (GD)
• Hashimoto thyroiditis (HT)
• Idiopathic membranous nephropathy (IMN)
• IgA nephropathy (IgAN)
• Lyme borreliosis
• Multiple sclerosis (MS)
• Rheumatoid arthritis (RA)
• Systemic lupus erythematosus (SLE)
• Vitiligo

This test is £275.  To order this test, please call or WhatsApp us on 07956004434

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